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Coagulation profile in COVID-19

Author(s)
Ambreen Kashif Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Sadia Taj Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Saira Moin Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Syeda Arzinda Fatima Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Ayaz Lone Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Qasim Ahmed Department of Pathology, Hematology and Medicine, Fatima Memorial Hospital, Lahore, Pakistan
Abstract
Objective: To evaluate the coagulation profile in COVID-19 patients and to correlate disease severity with the coagulation parameters. Methodology: This retrospective study was conducted at Pathology and medicine departments, FMH College of Medicine and Dentistry. It included 101 confirmed cases of COVID-19 disease of both genders between 17 and 75-year age. Coagulation profile was compared between survivor and nonsurvivor groups. Results: Out of 101 patients, 93 (92.1%) patients were in the survivor group and eight (7.8%) in the non-survivor group. Mean APTT (p = 0.02) in nonsurvivor group showed relatively higher values than survivor group. Mean D-Dimers (p = 0.007) in nonsurvivors showed a significantly raised values. However other parameters of coagulation like Platelets, MPV, PT and INR showed no significant association statistically. Conclusion: High D-dimers and prolonged APTT were associated with mortality in COVID-19 Patients.
Publication Details
Page(s) 523-526
DOI DOI not available
Published Journal: Rawal Medical Journal, Volume: 47, Issue: 3, Year: 2022

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Keywords
APTT, D-dimer, Coagulation, COVID-19.
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