C-reactive protein and low density lipoprotein as predictive marker for myocardial infarction

Farheen Shaikh; Shakeel Ahmed Shaikh; Ali Raza Memon; Abdul Sattar Khan; Ateeq Ur Rahman Surahio; Muhammad Ishaque Bhatti

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C-reactive protein and low density lipoprotein as predictive marker for myocardial infarction

Author(s)

Farheen Shaikh Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Shakeel Ahmed Shaikh Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Ali Raza Memon Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Abdul Sattar Khan Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Ateeq Ur Rahman Surahio Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Muhammad Ishaque Bhatti Department of Biochemistry, Peoples University of Medical and Health Sciences for women, Civil Hospital Pretabad, LUMHS, Jamshoro, Pakistan

Abstract

Objective: To determine C-reactive protein (CRP) & Low Density Lipoprotein as predictive marker for myocardial infarction. Methodology: A case-control study was conducted at Department of Medicine and Cardiology, Civil Hospital Matiari and Hala New Hyderabad from January to December 2018. It included 100 subjects with age between 15 to 65 years. Exclusion criteria was subjects suffering from systemic diseases. They were divided into two groups group A (Control) & group B (case study), each having 50 subjects; 50 healthy and 50 diagnosed with myocardial infarction (MI). Serum LDL & CRP were measured by auto analyzer and ELISA kit method, respectively. Results were analyzed by SPSS 16. Results: There was significant rise in CRP and LDL (p=<0.001), in case group as compared to control group. Conclusion: CRP is the best predictive marker for ischemic heart disease, especially myocardial infarction. LDL is good indicator of atherosclerosis rather than MI.

Publication Details

Page(s) 810-812

DOI DOI not available

Published Journal: Rawal Medical Journal, Volume: 46, Issue: 4, Year: 2021

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Keywords

LDL, CRP, atherosclerosis, Ischemic Heart Disease, Myocardial infarction.