Degradation/removal of pollutant using layered double hydroxide (LDHs) are currently attractive research topic for the remediation of polluted environmental systems, because of its low price and have anion exchange capability. The Ca-Cr LDH nanoparticle was prepared by co-precipitation method. This nanocomposites material is found to be favorable for removal of Cr (VI) from aqueous solution with over 96% removal being achieved within 10 min. Studies of effect of hydrochemistry on the sorption process such as initial solution pH, and organic load contamination interference, indicated nominal effect on the amount of chromium (VI) removed by the LDH. Overall, the study indicated that ion-exchange are active contributory mechanisms to the sorption of Cr (VI) by Ca/Cr LDH from solution. The precursor LDH and their metal oxide were characterized by using technique Infrared spectroscopy (IR), X-ray diffraction (XRD) and Ultraviolet spectroscopy (UV) spectroscopy.