Under laboratory conditions, aqueous, acetonic and methanolic extracts of Solanum nigrum, Atropa belladonna, Hyoscyamus muticus, Capsicum frutescens, Datura innoxia and Withania somnifera were tested against root-knot nematode, Meloidogyne javanica. All the tested materials afected the survival of the nematode juveniles and egg-masses hatched depending on materials property, concentrations and solvents used in extraction. The aqueous extract had the best percentage of mortality and inhibition of egg hatching compared to the acetonic and methanolic extracts. Whereas, aqueous extracts of deadly nightshade, winter cherry and chili pepper at concentration 500 ppm applied to the plants as foliar sprays alone, foliar sprays with chelates and soil drenches were tested against root-knot nematode M. javanica infecting tomato plants cv. Strain-B under greenhouse conditions. Almost tested materials have significantly reduced nematode parameters compared to Oxamyl 24% L. and the untreated plants (check). The degree of nematode reduction varied according to the method of applications and the type of materials. Adding the extract with the chelating nutrients improved the properties of the plant, but adding the extract as doses to the soil reduced the numbers of nematodes better than other methods of application.