Color-blindness is a genetic eye disease. The person who is suffering from this disease cannot see the correct color of life. The human eye consists of rods and cones. Rods are responsible for black and white vision while cones are responsible for color vision. Colorblindness is arisen due to a deficiency of few cones of the eye. E-Commerce application plays an important role in the current era. But most known applications do not handle colorblind people. In the existing research, there is no such solution suggested however in this research an Ontology is proposed for Ecommerce applications that assist color-blind people. The proposed ontology provides an understanding of the domain of color-blind disease and the E-commerce domain. The proposed ontology can be visualized by using the OWLViz tool. Validation of this ontology is provided by using a case study. This ontology can be further expanded by adding more concepts to it. This ontology can also be used by any GUI-based application by applying minor changes in concepts.