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Streptococcal Pharyngitis: Delving Deeper than the Throat

Author(s)
Sadaf Sheikh Department of Emergency Medicine, Sultan Qaboos University Hospital,Muscat,Oman
Umair Javed Department of Emergency Medicine, Aga Khan University Hospital,Karachi,Pakistan
Muhammad Akbar Baig Department of Emergency Medicine, Aga Khan University Hospital,Karachi,Pakistan
Abstract
Acute rhabdomyolysis and elevated transaminases during streptococcal pharyngitis are rare presentations. The proposed pathophysiological mechanisms include direct bacterial invasion and toxin generation. Physicians should be aware of the association between these infections and the above-mentioned complications to facilitate optimal treatment of these patients. We present the case of a 18-years-old gentleman with ²-haemolytic streptococcal pharyngitis complicated by rhabdomyolysis and elevated liver function tests. Such high levels of creatine phosphokinase of 111856 IU/L and elevated liver function tests with aspartate aminotransferase (AST) of 1862 U/L and alanine aminotransferase (ALT) of 1003 U/L instreptococcal pharyngitis is rare to nd in the literature. He was treated with aggressive intravenous hydration, antibiotics and hemodialysis.
Publication Details
Page(s) 732-734
DOI DOI not available
Published Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 31, Issue: 6, Year: 2021

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Keywords
liver function tests, Rhabdomyolysis, Creatine Phosphokinase, ²-haemolytic Streptococci
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