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Metal toxicity I: Cadmium.

Author(s)
N. Sheikh Department of Zoology, University of Punjab, Lahore, Pakistan
R. Abid Department of Zoology, University of Punjab, Lahore, Pakistan
I. A. Malik Department of Internal Medicine, University Hospital, Georg-August-University, Gottingen, Germany
Abstract
Cadmium (Cd) is a naturally occurring inorganic metal in the environment. It accumulates in the body with varying degrees of toxicity by replacing the body’s stores of the essential mineral zinc in the liver and kidneys. Cd occurs as cadmium salts, used in the production of colored inks, dyes, metal plating, engraving, soldering, plastics and nickel-Cd batteries with trace amounts of Cd in food. Daily intake of Cd should not exceed 7 mcg/kg of body weight per week. Regular smokers are at the risk of high exposure to Cd that results severe health problems. Another means of exposure to Cd is inhalation of fumes and dust irritating to lungs causing health problems. Elevated levels of Cd in human body results in hypertension (high blood pressure); a dulled sense of smell; anemia; yellow discoloration of the teeth; inflammation of mucous membrane of the nose (rhinitis); joint soreness; hair loss; dry, scaly skin; and loss of appetite, Cadmium toxicity threatens the health of the body by weakening the immune system. Cadmium is retained in the kidneys, liver mainly and also in the other organs. Excessive exposure can lead to kidney and serious liver damage. Possible effects of intense Cd exposure include emphysema, bone disorders such as osteoporosis and osteomalacia, canacer, and a shortened life span.
Publication Details
Page(s) 55-59
DOI DOI not available
Published Journal: Pakistan Journal of Science, Volume: 61, Issue: 1, Year: 2009

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