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Effect of thyroid hormone replacement on respiratory function tests in hypothyroid women.

Author(s)
Roopam Bassi Department of Physiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India
Sukhjinder Kaur Dhillon Department of Physiology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India
Saurabh Sharma Dermatology and Venereology, Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, India
Aditi Sharma Department of Biochemistry, Himalayan Institute of Medical Sciences, Dehradun, India
Mugdha Tapdiya Department of Medicine, Sri Guru Ram Das Institute of Medical Sciences & Research, Amritsar, India
Abstract
Background: Respiratory system, like other body systems and organs, is affected by hypothyroidism. Many patients of hypothyroidism complain of fatigue and exercise intolerance. These might be due to limited pulmonary reserve. This study was carried out to observe FVC, FEV1, FEV1/FVC and PEF in hypothyroid Punjabi women grouped on the basis of duration of treatment received. Methods: Twentysix recently diagnosed hypothyroid women (Group-A), and 22 hypothyroid women taking medication for the last 6–8 months (Group-B) were subjected to estimation of FVC, FEV1, FEV1/FVC and PEF and compared with 25 apparently euthyroid subjects (Group-C). They were also assessed for serum T4 and serum TSH. Data were analysed by One-way ANOVA with Post-Hoc Tukey HSD and Pearson’s correlation. Results: The mean values for FVC, FEV1 and PEF were more in treated hypothyroid subjects and euthyroid controls compared to untreated hypothyroid patients and the differences were highly significant (p
Publication Details
Page(s) 20-23
DOI DOI not available
Published Journal: Pakistan Journal of Physiology, Volume: 8, Issue: 2, Year: 2012

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