Cloud Computing (CC) is an innovative computing model in which resources are provided as a service over the Internet, on an as-needed basis. It is a large-scale distributed computing paradigm that is driven by economies of scale, in which a pool of abstracted, virtualized, dynamically-scalable, managed computing power, storage, platforms, and services are delivered on demand to external customers over the Internet. Since cloud is often enabled by virtualization and share a common attribute, that is, the allocation of resources, applications, and even OSs, adequate safeguards and security measures are essential. In fact, Virtualization creates new targets for intrusion due to the complexity of access and difficulty in monitoring all interconnection points between systems, applications, and data sets. This raises many questions about the appropriate infrastructure, processes, and strategy for enacting detection and response to intrusion in a Cloud environment. Hence, without strict controls put in place within the Cloud, guests could violate and bypass security policies, intercept unauthorized client data, and initiate or become the target of security attacks. This article shines the light on the issues of security within Cloud Computing, especially inter-VM traffic visibility. In addition, the paper lays the proposition of an Application Based Security (ABS) approach in order to enforce an application-based authentication between VMs, through various security mechanisms, filtering, structures, and policies.