Thyroid Dysfunction and its effect on Serum Lipids.

Shahnaz Attaullah; Imdadullah Mohammadzai; Jawad Ahmad; Bibi Safia Haq; Umair Wadood

Author(s)

Shahnaz Attaullah Department of Bio-Chemistry, Jinnah College for Women, University of Peshawar, Pakistan

Imdadullah Mohammadzai Department of Bio-Chemistry, Jinnah College for Women, University of Peshawar, Pakistan

Jawad Ahmad Department of Bio-Chemistry, Jinnah College for Women, University of Peshawar, Pakistan

Bibi Safia Haq Department of Bio-Chemistry, Jinnah College for Women, University of Peshawar, Pakistan

Umair Wadood Department of Bio-Chemistry, Jinnah College for Women, University of Peshawar, Pakistan

Abstract

Objectives: To evaluate the incidence of thyroid dysfunction and to investigate the chemical changes in serum lipids under the influence of thyroid dysfunctions. Material and Methods: This study was conducted in Pakistan Medical Research Centre (PMRC), Khyber Medical College, Peshawar, Pakistan from January 2011 to August 2014 . Blood samples and data were collected from patients attending the Institute of Radioactive Nuclear Medicine (IRNUM) Peshawar, Pakistan. A Total of 600 cases were included in this study out of which 214 were euthyroid, 195 and 191 were hyperthyroid and hypothyroid respectively. Results: The study subjects are divided into three groups on the basis of hormonal assay for the three parameters i.e. thyroid stimulating hormone (TSH), tri-iodo thyronine (T3), tetra-iodo thyronine (T4). The Euthyroid group which includes healthy individuals serves as control. The level of significance chosen as 0.05 and p-values were calculated. Conclusion: Thyroid dysfunctions are more prevalent in females, total Cholesterol (TC), Triglyceride (TG) and Low Density Lipo Protein Cholesterol (LDL-C) levels are positively correlated with hyperthyroidism as well as hypothyroidism, whereas High Density Lipo Protein Cholesterol (HDL-C) has no significant relation with thyroid dysfunction.

Publication Details

Page(s) 34-37

DOI DOI not available

Published Journal: Journal of Medical Science, Volume: 23, Issue: 1, Year: 2015

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