99mTc-labelled hepatoiminodiacetic acid (HIDA) scintigraphic evaluation of prevalence of biliary atresia in children with persistent neonatal jaundice: a comparison with national, regional & international studies. | Pakistan Journal of Nuclear Medicine 2014

Author(s)

Muhammad Inamullah Nuclear Medical Centre, Armed Forces Institute of Pathology (AFIP), Rawalpindi, Pakistan

Mujahid Khalid Ali Nuclear Medical Centre and Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan

Tariq Mahmood Mirza Nuclear Medical Centre and Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan

Muhammad Omair Riaz Nuclear Medical Centre and Department of Immunology, Armed Forces Institute of Pathology, Rawalpindi, Pakistan

Abstract

Aims This retrospective study aimed at determining the prevalence of biliary atresia in children presenting with persistent neonatal jaundice by technetium-99m labelled hepatoimino diacetic acid (99mTc-HIDA) scintigraphy. The results were compared with those from similar studies conducted in Pakistan, South East Asia & internationally. Methods The study was conducted at Nuclear Medicine Centre, Armed Forces Institute of Pathology, Rawalpindi, from June 2010 to December 2012. A total of 80 patients with persistent neonatal jaundice were included in the study with 54 males & 26 females in a ratio of about 2 to 1. Main outcome measure was demonstration of biliary atresia on technetium-99m labelled hepatoiminodiacetic acid (99mTc-HIDA) scan. Results Patients with a clinical diagnosis of persistent neonatal jaundice were included in the study. The mean age for males and females at presentation was 224 & 122 days respectively. Biliary atresia was diagnosed in 45 patients with 28 being male and 17 female patients respectively. Conclusion A significant percentage of patients (56.25%) presenting with persistent neonatal jaundice are found to have biliary atresia on scintigraphic evaluation.

Publication Details

Page(s) 40-45

DOI DOI not available

Published Journal: Pakistan Journal of Nuclear Medicine, Volume: 4, Issue: 1, Year: 2014

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