Affect of combined oral contraceptives on routine coagulation parameters. | Proceedings of sheikh zayed postgraduate medical institute 2004

Author(s)

Ghazanfar Ali Sirhindi Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Muhammad Javed Asif Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Saadia Shahzad Alam Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Nasir M. Chughtai Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Zafar Iqbal Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Abdul Hameed Khan Department of Pathology, Federal Postgraduate Medical Institute, Shaikh Zayed Hospital, Lahore, Pakistan

Abstract

The present study was designed to estimate the coagulation parameters like fibrinogen degradation products (FDPs), fibrinogen levels, thrombin time (TT), Prothrombin time (PT) and activated partial thromboplastin time (APTT). In this study, 40 subjects on combined oral contraceptives (COCs) with a contraceptive duration from 3-18 months and 20 normal females without hormonal contraceptives were included. Blood samples were collected for coagulation parameters in accordance with the standard protocol. FDPs and fibrinogen levels were significantly elevated whereas PT, APTT and TT were shortened in subjects using combined oral contraceptives (COCs) as compared to normal controls.

Publication Details

Page(s) 1-5

DOI DOI not available

Published Journal: Proceedings of sheikh zayed postgraduate medical institute, Volume: 18, Issue: 1, Year: 2004

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