Pressure ulcers (PU) are common international afflictions that occur in many different healthcare settings. The aim of this prospective, randomized, multi-center study was to determine the effectiveness of micro-current (MCT) therapy on patients with four chronic stages under the National Pressure Ulcer Advisory Panel (NPUAP). PU on 60 male and female patients enrolled from 6 hospitals. The analysis reveals that MCT has a significant effect on wound healing. Data analysis also reveals that wounds of female patients are healed significantly faster than those of male patients and that age significantly influenced wound healing.