A retrospective, observational study to assess the intermediate-term clinical outcomes of COVID-19 patients in a tertiary hospital in Khyber Pakhtunkhwa, Pakistan | Anaesthesia, Pain and Intensive Care 2024

Author(s)

Muhammad Sheharyar Ashraf Department of Anesthesia & Critical Care Unit Lady Reading Hospital-MTI,Peshawar,Pakistan

Arishay Hussaini Department of Critical Care Medicine, Ziauddin University,Karachi,Pakistan

Dilanthi Priyadarshani Gamage Dona Department of Statistics, National Intensive Care Surveillance-MORU (NICS-MORU),Colombo,Sri Lanka

Mohiuddin Shaikh South East Asian Research in Critical Care Health (SEARCH),Karachi,Pakistan

Abstract

Background & Objective: There is limited data from lower middle-income countries to describe the outcomes of COVID-19 and the prevalence of patients requiring critical care. We aim to assess and compare the demographics, clinical course and mortality of COVID-19 patients admitted to the intensive care unit (ICU) and those admitted to the specialized COVID unit (SCU). Methodology: A single-center, retrospective, observational study in which all patients admitted to Lady Reading Hospital (LRH), Peshawar (Pakistan) with laboratory-confirmed COVID-19 from March 25, 2020 to December 31, 2021 were included. Study data were retrieved through the Pakistan Registry of Intensive Care (PRICE). Results: Of 699 patients, 448 were critically ill, and 251 did not require ICU admission. Of those admitted to ICU, 61.8% were male, with a median age of 55 y. ICU mortality was significantly higher (P = 0.001) among those on IMV and those aged 60 y; whereas 68.9% of the non-ICU patients were male, with a median age of 57 y. While the median duration of hospitalization was significantly longer (P = 0.001), the chances of recovery were substantially better (P = 0.001) compared with the critically ill population. Conclusion: The major risk factors contributing to the increased mortality in COVID-19 patients are age and the requirement for IMV.

Publication Details

Page(s) 198-205

DOI 10.35975/apic.v28i2.2423

Published Journal: Anaesthesia, Pain and Intensive Care, Volume: 28, Issue: 2, Year: 2024

Keywords

COVID19 SARSCoV2 Mortality Intensive care unit Lower middle income country Covid19

References

Huang C,Wang Y,Li X,Ren L,Zhao J,Hu Y .2020 .General's opening remarks at the media briefing on. [cited 2023 Aug, 9(20) : 30183-5.

Peters AW,Chawla KS,Turnbull ZA,Arentz M,Yim E,Klaff L,Lokhandwala S,Riedo FX,Chong M,Jaillon S,Berthenet K,Garlanda C .2020 .Sexual Dimorphism in Innate Immunity. 2019 Jun, 30(3) : 308-21.

Chaudhry A,Ikram A,Baig MA,Salman M,Ghafoor T,Hussain Z,Medetalibeyoglu A,Senkal N,Kose M,Catma Y,Bilge Caparali E,Erelel M,Dhochak N,Singhal T,Kabra SK,Lodha R,Yang SS,Lipes J,Dial S,Schwartz B,Laporta D,Wong E .2020 .Older Adults Hospitalized with COVID-19: Clinical Characteristics and Early Outcomes from a Single Center in Istanbul, Turkey. 2020 Jul, 14(7) : 537-46.

. .Outcomes and clinical practice in patients with COVID-19 admitted to the intensive care unit in Montréal, Canada: a descriptive analysis. CMAJ Open, 8(4) : E788-95.

Bepouka B,Odio O,Mangala D,Mayasi N,Mandina M,Longokolo M . .Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis. Cureus. 2022 Jul, 15(7) : e26877.

Zerah L,Baudouin É,Pépin M,Mary M,Krypciak S,Bianco C,Garcia-Gallo E,Merson L,Kennon K,Kelly S,Citarella BW,Data Sci . .ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19. 2022 Jul, 30(1) : 454-12.

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