A histopathological and epidemiological study of urothelial carcinoma at a tertiary care centre in Peshawar, Pakistan | Journal of Pakistan Medical Association 2024

Author(s)

Saria Saeed Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Danyal Khan Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Shah Faisal Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Fozia Rauf Department of Pathology, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Muhammad Owais Ali Department of Surgery, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Asif Rehman Department of Community Health Sciences, Peshawar Medical College, Riphah International University, Peshawar, Pakistan

Abstract

Bladder cancer is the ninth leading cause of death worldwide and 14th leading cause of death in Pakistan. The objective of this study was to determine the frequency of urothelial carcinoma in various age groups, its gender distribution, and grades. A total of 131 cases of urothelial carcinoma, received at Department of Pathology, Peshawar Medical College, Peshawar, between January 2017 to December 2022, were included in the study; of them 107 (81.6%) were males while 24 (18.3%) were females with a mean age of 62±13 years. The most common histological subtype was papillary urothelial carcinoma in 117(89.3%) cases, followed by Squamous and Glandular in 5(3.8%) cases. Majority of the urothelial carcinoma with high grade showed a statistically signifi cant relation with muscle invasion 38 (50.66%). Males were four times more likely to have urothelial carcinoma while older age groups were more likely to have high grade urothelial carcinoma.

Publication Details

Page(s) 1160-1162

DOI 10.47391/JPMA.9546

Published Journal: Journal of Pakistan Medical Association, Volume: 74, Issue: 6, Year: 2024

Keywords

Cancer Carcinoma Urinary bladder Neoplasm Urothelial

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