Antimicrobial screening of some derivatives of methyl a-D-glucopyranoside. | Pakistan Journal of Scientific and Industrial Research 2009

Author(s)

Abul K. M. S. Kabir Department of Chemistry, University of Chittagong, Chittagong, Bangladesh

Sarkar M. A. Kawsar Department of Chemistry, University of Chittagong, Chittagong, Bangladesh

Mohammad M. R. Bhuiyan Department of Chemistry, University of Chittagong, Chittagong, Bangladesh

Mohammad E. Ghowdhury Department of Chemistry, University of Chittagong, Chittagong, Bangladesh

Md. Safiq-Ur-Rahman Department of Microbiology, University of Chittagong, Chittagong, Bangladesh

Abstract

In vitro antimicrobial functionality test of methyl 4,6-O-cyclohexylidene-α-D-glucopyranoside and its twelve acylated derivatives against ten human pathogenic bacteria and six phytopathogenic fungi comparative to Ampicillin and Nystatin revealed the tested chemicals to possess moderate to good antibacterial and antifungal activity and to be more effective against fungal phytopathogens. Many of these chemicals exhibited better antimicrobial activity than the standard antibiotics. Minimum Inhibition Concentration (MIC) of methyl 4,6-O-cyclohexylidene-2-O-myristoyl-3-O-palmitoyl-α-D-glucopyranoside against Bacillus cercus, Bacillus subtilis and Staphylococcus aureus was 25, 12.5 and 25 µg/disc, respectively.

Publication Details

Page(s) 138-142

DOI DOI not available

Published Journal: Pakistan Journal of Scientific and Industrial Research, Volume: 52, Issue: 3, Year: 2009

Keywords

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