Casting Zinc Oxide nanoparticles using Fagonia blend microbial arrest | Abstract Book on Global Science Technology and Management Conference 2023

Riaz Hussain Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan

Ayesha Zafar Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan; Department of Biomedical Engineering, College of Future Technology, Peking University, Beijing 100871, China

Murtaza Hasan Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan; School of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Tuba Tariq Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

M. Saqib Saif Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

M. Waqas Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Fatima Tariq Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Muniba Anum Department of Biotechnology, IBBB, The Islamia University of Bahawalpur, Bahawalpur, Pakistan

Syed Ishtia Anjum Department of Zoology, Kohat University of Science and Technology, Kohat, Pakistan

Xugang Shu School of Chemistry and Chemical Engineering, Zhongkai University of Agriculture and Engineering, Guangzhou 510225, China

Physical and chemical methods for production of nanoparticles (NPs) are not only harmful for environment but also toxic for living organism. The present study attempts to synthesize ZnO NPs using the natural plant extract of Fagonia cretica. The phytochemical screening of F. cretica water extract was performed to check the presence of biologically active compounds like alkaloids, tannins, carbohydrates, proteins, phenols, saponins, flavonoids, and steroids. Well-prepared ZnO NPs given sharp absorption peak at 362 were confirmed by UV-visible. XRD analysis showed the ZnO NPs having wurtzite hexagonal structure with crystalline form. TEM analysis endorses flower-shaped ZnO nanoparticles ~ 100-1000 nm. FTIR spectrum suggested the involvement of phenolic groups and amino acids and amide linkages in protein performs as the stabilizing agent in the synthesis of ZnO NPs. The ZnO NPs showed strong antibacterial behavior against two bacterial strains Gram-positive bacteria Staphylococcus aureus and Gram-negative bacteria Escherichia coli. In addition, ZnONPs exhibited strong antioxidant activity of 79%:85.6%:89.9% at 5 µg/mL:10 µg/mL:5 µg/ mL concentration of ZnO NPs respectively. This work indicates that Fagonia is considered to be appropriate and promising candidate for extending the innovative applications in the field of medicine and industry and also helpful and useful to the scientific communities.