Article Detail — Pakistan Science Abstracts

Choose Theme

Theme 1 — Green & Gold

No Detail Found!
A clinical audit to evaluate antibiotic prescribing practice in pediatric patients admitted for enteric fever. Rationalizing antibiotic stewardship program
Author(s)
Abdullah Hussain Pediatric Medicine Department, Services Hospital,Lahore,Pakistan
Usman Asghar Pediatric Medicine Department, Services Hospital,Lahore,Pakistan
Iram Asghar Gill Sahiwal Medical College,Sahiwal,Pakistan
Maryam Shahid Mayo Hospital,Lahore,Pakistan
Ayesha Shahid Shaikh Zayed Hospital,Lahore,Pakistan
Muhammad Nabeel Hassan Pediatric Medicine Department, Services Hospital,Lahore,Pakistan
Iftikhar Ali Pediatric Medicine Department, Services Hospital,Lahore,Pakistan
Fatima Naheed Shalamar Hospital,Lahore,Pakistan
Muhammad Numan Zahid Pediatric Medicine Department, Services Hospital,Lahore,Pakistan
Abstract
To evaluate the antibiotic prescribing practice in pediatric patients for enteric fever, and to assess the need of developing and implementing the Antibiotic Stewardship Program (ASP) for the hospital. A prospective audit was completed in the pediatric ward of tertiary care hospital of Lahore for one year. Blood culture reports were collected from microbiology departed and clinical data were assessed regarding the choice of antibiotics, frequency, dosage and clinical outcome. All the statistics were analyzed using SPSS software and compared with the guidelines. Out of 157 cases hospitalized with suspicion of enteric fever, 137 cultures were positive for salmonella. Monotherapy of ceftriaxone (70%) was prescribed mostly as empirical therapy. About 20% of patients received a combination of antibiotics empirically. Susceptibility reports showed only 7 cases were of non-resistant typhoid, 15 multi-drug resistant and 115 extensively drug-resistant. Nearly 46% of patients were discharged earlier whose empirical therapy was changed either before or promptly after susceptibility reporting. Commonly used definitive antibiotics (32%) were a combination of azithromycin and meropenem. Inappropriate use of antibiotics was noted frequently as compared to the guidelines. However, recommendations themselves need to be reviewed as antibiotic resistance patterns are changing drastically.
Publication Details
Page(s) 993-997
DOI 10.36721/PJPS.2022.35.4.REG.993-997.1
Published Journal: Pakistan Journal of Pharmaceutical Sciences, Volume: 35, Issue: 4, Year: 2022
Keywords
Typhoid fever Clinical audit antibiotic protocols
References
References are not available for this document.
Citations
Citations are not available for this document.
0

Citations

0

Downloads

136

Views

Copyright ©  PASTIC National Center, Islamabad www.pastic.gov.pk