8p11 associated myeloid/lymphoid neoplasms: An illustrative case report of this rare entity and review of literature | Journal of Pakistan Medical Association 2020

Author(s)

Naeem Jabbar Department Pediatric Oncology, Indus Health Network, Karachi, Pakistan.

Neelum Mansoor Indus Health Network, Karachi, Pakistan; Department of Haematology, Indus Health Network, Karachi, Pakistan.

Momal Taimoor Indus Health Network, Karachi, Pakistan; Department of Haematology, Indus Health Network, Karachi, Pakistan.

Omer Jawed Indus Health Network, Karachi, Pakistan; Department of Haematology, Indus Health Network, Karachi, Pakistan.

Muhammad Shamvil Ashraf Department Pediatric Oncology, Indus Health Network, Karachi, Pakistan.

Abstract

This report describes a unique case of 8p11 myeloproliferative syndrome (EMS), also known as stem cell leukaemia-lymphoma syndrome. A 13 years old male was referred from a tertiary care hospital after cervical lymph node biopsy. The disease mechanism of this neoplasm is to either evolve into acute myeloid leukemia or mixed lineage leukaemia, and less frequently of T or B lymphoid lineage. However, here we show a case of a rare simultaneous presentation of T lymphoblastic lymphoma on cervical lymph node and B lymphoblastic leukaemia on bone marrow biopsy along with t (8; 13) on karyotype testing.

Publication Details

Page(s) 743-746

DOI DOI not available

Published Journal: Journal of Pakistan Medical Association, Volume: 70, Issue: 4, Year: 2020

Keywords

Karyotype T lymphoblastic lymphoma t 8 B lymphoblastic leukemia FGFR1

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