ROLE OF TOPICAL NEPAFENAC IN PREVENTING INCREASE IN MACULAR THICKNESSAFTER PHACOEMULSIFICATION | Journal of Postgraduate Medical Institute 2020

Author(s)

Wali Ullah Department of Ophthalmology,Hayatabad Medical Complex, Peshawar, Pakistan

Muhammad Irfan Department of Ophthalmology,Hayatabad Medical Complex, Peshawar, Pakistan

Shahid Abdur Rauf Khan Department of Ophthalmology,Hayatabad Medical Complex, Peshawar, Pakistan

Adnan Ghalib Alshifa Trust Eye Hospital,Kohat -, Pakistan

Zia uddin Khalil⁵ Department of Ophthalmology,Hayatabad Medical Complex, Peshawar, Pakistan

Abstract

To compare mean increase in macular thickness in patients using topical Nepafenac and standard treatment with standard treatment alone, after phacoemulsifation. Methodology: This was a comparative cross sectional study which involved 84 patients operated for age related cataracts. Pre-operative optical coherence tomography (OCT) was performed to document the central macular thickness and patients were randomly allocated to 2 groups. Group A received topical Nepafenac 0.1% in addition to the standard post-operative topical medication. Group B received only standard regimen of topical medications including antibiotics and steroids. Phacoemulsification was performed in both groups. A post-operative OCT was done to observe the central macular thickness after 2 months of surgery. The mean increase in central macular thickness was compared between the two groups. Data were analyzed utilizing SPSS version 20.0. Results: Phacoemulsification was performed in 84 patients, males were 45 (53.57%) and 39 (46.42%) were female patients. Average age was 58.65 ±6.01 years. The mean increase in macular thickness was 6.85 ± 4.69um. There was statistically significant difference between the two groups with respect to mean post-operative macular thickness and mean increase in macular thickness (p value <0.01). Conclusion: Topical Nepafenac 0.1% was associated with less mean increase in macular thickness after cataract surgery. .

Publication Details

Page(s) 253-258

DOI DOI not available

Published Journal: Journal of Postgraduate Medical Institute, Volume: 34, Issue: 4, Year: 2020

Keywords

Nepafenac Phacoemulsification Cystoid macular edema Central macular thickness

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