The relation of glycosylated hemoglobin levels with hemoglobin levels in non diabetic patients having iron deficiency anemia | Journal of Medical Science 2020

Author(s)

Safia Rahman Department of Chemical Pathology, Khyber Teaching Hospital,Peshawar -,Pakistan

Muhammad Ihtesham Khan Department of Hematology, Khyber Medical College,Peshawar -,Pakistan

Samiya Rahman Department of Pathology, Khyber Medical College,Peshawar -,Pakistan

Saman Waqar Department of Chemical Pathology, Federal Medical and Dental College,Islamabad -,Pakistan

Abstract

Objective: To determine the relationship between levels of glycosylated hemoglobin and hemoglobin levels in non diabetic patients having iron deficiency anemia. Material and Methods: This Cross-sectional descriptive study was conducted in Pathology department of Khyber Teaching Hospital,Peshawar-Pakistan from January 2019 to November 2019. Non diabetic cases with iron deficient anemia were in cluded in study. The hemoglobin level of less than 13 gm /dl in males and less than 12 gm per dL for females was taken as cut off for anemia. The mean cell volume of less than 75 fl was taken as a cut off for iron deficiency anemia. The hematologist confirmed the cases to have iron deficiency anemia and analysed the blood counts. glycated hemoglobin A levels were detected in all the cases using Cobaschemillumniscent 411-E equipment by consultant chemical pathologist. Pearson correlation test and linear regression model were used to determine correlation between hemoglobin levels and HbA1c levels . Results: Fourty eight non-diabetic cases with iron deficiency anemia were included in the study. Mean age of the population was 38±8.9 years (range :12-70 years). There were 17 (35.4%) males and 31(64.6%) females. HbA1C levels were high in 35 (72.9 %) cases, normal in13 (27.1 %). Pearson-r test showed a weak negative correlation ( r=-.077, n=48, p=.604 ). Linear regression model was applied which showed that HbA1C levels can not be predicted for a given hemoglobin value ( R2 =-.016, p value= .604 ) Conclusion: There is no significant correlation between hemoglobin levels and HbA1c levels in non diabetics.

Publication Details

Page(s) 176-180

DOI DOI not available

Published Journal: Journal of Medical Science, Volume: 28, Issue: 2, Year: 2020

Keywords

Iron deficiency Glycated hemoglobin A Anemia hemoglobins

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