An effective combined therapy of meglumine antimoniate and co-trimoxazole for cutaneous leishmaniasis: A study in Quetta City. | [Journal of Pakistan Association of Dermatologists • 2014]

Author(s):

1. Bilal Ahmed: Department of Dermatology, Bolan Medical College, Quetta, Pakistan

2. Muhammad Iqbal Tareen: Department of Dermatology, Bolan Medical College, Quetta, Pakistan

3. Ashok Kumar: Department of Pathology, Isra University, Hyderabad, Pakistan

4. Saira Baloch: Medical Research Centre, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

5. Hazir Rehman: Medical Research Centre, Liaquat University of Medical and Health Sciences, Jamshoro, Pakistan

6. Zahid Mustafa: Centre for Advanced Studies in Vaccinology & Biotechnology (CASVAB), University of Baluchistan, Quetta, Pakistan

7. Abdul Malik Tareen: Centre for Advanced Studies in Vaccinology & Biotechnology (CASVAB), University of Baluchistan, Quetta, Pakistan

Abstract:

Objective To evaluate the efficacy of combined therapy of meglumine antimoniate and cotrimoxazole in cutaneous leishmaniasis (CL). Methods 180 patients with active lesions of CL, confirmed by fine needle aspiration cytology (FNAC) were treated with combined therapy of meglumine antimoniate (Glucantime) and cotrimoxazole (Septran) for 20 days. Results Out of 180 patients, 160 (88.9%) were cured. A few patients reported nausea, vomiting, glossitis, skin rashes and folate deficiency. Conclusion The combined therapy of meglumine antimoniate (Glucantime) and co-trimoxazole (Septran) is more effective than the previously reported combined therapies.

Page(s): 122-126

DOI: DOI not available

Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 24, Issue: 2, Year: 2014

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