Abstract:
Common definitions of cancer include unchecked cell growth, loss of differentiation, and frequent metastasis, or the spread of the tumor to other tissues and organs. Smoking, drinking too much alcohol, chewing tobacco, an unbalanced diet, and other factors all contribute to the development of cancer. Synthetic anticancer medications include mechlorethamine, mercaptopurine, fluorouracil, paclitaxel, etoposide, and others. More than 1000 plants have been identified to have substantial anticancer effects in the context of cancer treatment. Certain "lead" compounds have emerged as nature`s gift for cancer chemotherapeutic purposes because of chemical and biological investigations on some of them. Several improved analogues of these lead compounds have been created thanks to a knowledge of the mechanisms of action and the structure-activity relationship. While this review focuses on the Herbal anticancer medications are another option for cancer treatment that has fewer or no side effects than synthetic anticancer treatments. Due to their clearly outlined anticancer drug mechanisms of action, some herbal anticancer medications, such as Catharanthus roseus, Camptotheca acuminate, Podophyllum species, and Taxus species, are widely used. The use of these herbal medications against cancer as is or in their semi-synthetic counterparts is promoted by appropriate chemical and biological investigations, comprehension of the mechanisms of action, development of the structure activity relationship, and high yield manufacturing through plant tissue culture.
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Journal: Abstract Book on 9th Annual Neuroscience Conference (ANC-23) August 12-13, 2023 , Volume: 0, Issue: 0, Year: 2023