A case report of synchronous bilateral tonsillar carcinoma associated with human papilloma virus | [Journal of Pakistan Medical Association • 2021]

Author(s):

1. Muneki Hotomi: Department of Otolaryngology Head and Neck Surgery at Wakayama Medical niversity,Wakayama, Japan

2. Kenji Warigaya: Department of Human Pathology, Wakayama Medical University, Wakayama, Japan

3. Esra Gunduz: Department of Otolaryngology Head and Neck Surgery at Wakayama Medical niversity,Wakayama, Japan

4. Keisuke Enomoto: Department of Human Pathology, Wakayama Medical University, Wakayama, Japan

5. Mehmet Gunduz: Department of Human Pathology, Wakayama Medical University, Wakayama, Japan

6. Shunji Tamagawa: Department of Otolaryngology Head and Neck Surgery at Wakayama Medical University,Wakayama, Japan

Abstract:

The case of a 69-year-old man with bilateral synchronous tonsillar carcinoma is reported. The patient complained of nasal closure, strange voice, and discomfort in his pharynx when he was admitted to the Department of Otolaryngology Head and Neck Surgery at Wakayama Medical University, Wakayama, Japan, in March 2017. The palatine tonsils were enlarged and the surface was irregular. Left cervical lymphadenopathy was also evident. Histological examination from both tonsils was performed and bilateral tonsillar squamous cell carcinoma was diagnosed. PCR analysis showed the same HPV-DNA pattern from bilateral tonsils. Concurrent chemoradiotherapy was performed. Total 70 Gy of irradiation (2Gy/day×35 day) was applied to bilateral tonsillar tumours and upper neck. Follow up was conducted every three months and the patient was free of recurrence for three years. Patient's informed consent was taken to publish the case report.

Page(s): 352-355

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 71, Issue: 1, Year: 2021

Keywords:

bilateral synchronous tonsillar carcinoma , tonsil

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