Acute disseminated encephalomyelitis in a child following Plasmodium vivax malaria. | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2015]

Author(s):

1. Radheshyam Purkait: Department of Paediatric Medicine1/ Radiology2, NRS Medical College and Hospital, 138, AJC Bose Road, Kolkata, West Bengal, India

2. Aritra Mukherji: Department of Paediatric Medicine, NRS Medical College and Hospital, 138, AJC Bose Road, Kolkata, West Bengal, India

3. Tapankumar Sinhamahapatra: Department of Paediatric Medicine, NRS Medical College and Hospital, 138, AJC Bose Road, Kolkata, West Bengal, India

4. Ramchandra Bhadra: Department of Radiology, NRS Medical College and Hospital, 138, AJC Bose Road, Kolkata-700014, West Bengal, India

Abstract:

Acute Disseminated Encephalomyelitis (ADEM) is a multifocal, monophasic, acute demyelinating disease of the brain and spinal cord, which is commonly preceded by viral infections and occasionally bacterial infections or immunizations. Its occurrence following malarial infection, especially Plasmodium vivaxMalaria is very uncommon. We report an 11-year girl who presented with clinical features of encephalopathy and generalized convulsions, 10 days following complete recovery from the Plasmodium vivaxMalaria. Diagnosis of ADEM as a complication of Plasmodium vivaxMalaria was made based on acute onset of neurological events, characteristic findings on Magnetic Resonance Imaging (MRI) of brain and prompt response to corticosteroid therapy. Follow-up MRI, 6 months after discharge, showed complete resolution of change found on the initial MRI. To the best of our knowledge, only two such cases have been reported in the English literature till date.

Page(s): 538-540

DOI: DOI not available

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 25, Issue: 7, Year: 2015

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