Abstract:
Objectives: Tofind out the relative frequency of conditions associated with thrombocytopaenia. Study design: Descriptive study Place and Duration of study: Combined Military Hospital Attock in collaboration with Armed Forces Institute of Pathology Rawalpindi, from March 2003 to March 2004. Materials and Methods: All patients referred for blood counts. Patients with platelet count below 150x109/L, were registered. Investigations including peripheral blood counts and smear examination, blood/smear for bacterial culture, IgM for Dengue virus, Hepatitis B surface antigen and anti-hepatitis C Antibodies, ultrasound abdomen and bone marrow examination were performed. Results: Out of 18,000 patients, 415(2.3%) revealed thrombocytopaenia (341 adults and 74 children). In adults, viral anti-body was found in 27.7%, malaria in 17%, bacterial infections in 12.4%, megaloblastic anaemia in 8.2%, bone marrow infiltrates in 7.9%, drug induced thrombocytopaenia in 4.4%, chronic liver disease in 3.5%, hypersplenism in 2.9%, DIC in 2.9%, pregnancy associated thrombocytopaenia in 2%, aplastic anaemia in 1.5%, ITP in 1.2% and upper respiratory viral infection in 8%. In paediatric age group malaria was detected in 27%, megaloblastic anaemia in 23%, bacterial infections in 13.5%, leukaemia in 13.5%, neonatal thrombocytopaenia in 9.5%, ITP in 2.7%, DIC in 1.4%, aplastic anaemia in 1.4% and upper respiratory viral infections in 8%. Conclusion: Malaria, viral and bacterial infections and megaloblastic anaemia are the most common causes of thrombocytopaenia in our setup.
Page(s):
143-146
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Pathology, Volume: 15, Issue: 4, Year: 2004