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An overview of Treatment Options for Postoperative Nausea and Vomiting after Laparoscopic Surgical Procedures.
Author(s):
1. HseyinC Turgut: Department of Maxillofacial Surgery, Faculty of Dentistry, Gazi University, Ankara, Turkey
2. Mustafa Arslan: Department of Anesthesiology & Reanimation, Faculty of Medicine, Gazi University, Ankara, Turkey
Abstract:
Background: Postoperative nausea and vomiting (PONV) is a well-known entity following surgical procedures and may result in serious complications include aspiration of gastric contents, prolonged recovery period, impaired surgical wound healing. Laparoscopic surgery alone is a known risk factor for PONV and different treatment options with various agents are preferred for PONV prophylaxis and treatment. Aim: We aimed to review advantages and disadvantages of various drugs and combination regimens for prophylaxis and treatment of PONV after different types of laparoscopic procedures. Methodology: We made a comprehensive PubMed search using search terms PONV, laparoscopic surgery, prophylaxis, treatment, drug, without considering publication time period. Findings: Relatively traditional anti-emetics, including anticholinergics, antihistamines and phenothiazines, have more prominent side effect profiles. Using different receptor antagonists (serotonin 5-HT3, neurokinin, dopamine receptor antagonists) especially when combined with agents of same group or from various different groups, e.g. dexamethasone - a strong corticosteroid, naloxone - an opioid receptor antagonist, or propofol - an intravenous anesthetic and hypnotic, effective anti-emesis can be achieved. Conclusion: Combinations of antiemetic agents of different groups is more effective in prevention of postoperative nausea and vomiting.
Page(s): 193-200
DOI: DOI not available
Published: Journal: Anaesthesia, Pain and Intensive Care, Volume: 20, Issue: 2, Year: 2016
Keywords:
Keywords are not available for this article.
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