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Methods of Analysis of Riboflavin (Vitamin B2): A Review.
Author(s):
1. Wajiha Gul: Faculty of Pharmacy, Jinnah University for Women, Karachi-74600, Pakistan
2. Zubair Anwar: Baqai Institute of Pharmaceutical Sciences, Baqai Medical University (BMU), Karachi, Pakistan
3. Kiran Qadeer: Baqai Institute of Pharmaceutical Sciences, Baqai Medical University (BMU), Karachi, Pakistan
4. Shaheen Perveen: Faculty of Pharmacy, Jinnah University for Women, Karachi-74600, Pakistan
5. Iqbal Ahmad: Baqai Institute of Pharmaceutical Sciences, Baqai Medical University (BMU), Karachi, Pakistan
Abstract:
Riboflavin (vitamin B2) is a component of vitamin B complex and multivitamin preparations. It exhibits several physical properties, such as light absorption, florescence emission and electroreduction. These properties have been used to develop spectrometric, fluorimetirc, electrochemical, chromatographic and electrophoretic methods for the assay of riboflavin in pharmaceutical preparations and clinical samples. In addition to these enzymatic and microbiological methods have also been used for the assay of the vitamin. The fluorimetric methods are much more sensitive than the spectrometric methods. Chromatographic methods have the advantage of separation and simultaneous determination of riboflavin and other components of vitamin preparations. All the above mentioned methods have been reviewed.
Page(s): 10-21
DOI: DOI not available
Published: Journal: RADS Journal of Pharmacy & Pharmaceutical Sciences, Volume: 2, Issue: 2, Year: 2014
Keywords:
Chromatography , Electrophoresis , Fluorimetry , Spectrometry
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