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A prospective randomised double blind study comparing the efficacy of peri-articular injection with bupivacaine and levobupivacaine for postoperative pain control in total knee arthroplasty
Author(s):
1. Rohit Kumar Varshney: Department of Anesthesiology, Teerthankar Mahaveer Medical College, Moradabad, U.P, (India)
2. Najamul Huda: Department of Orthopedics, Teerthanker Mahaveer Medical College, Moradabad, U.P, (India)
Abstract:
Objective: Adequate control of postoperative pain management after total knee arthroplasty (TKA) remains a big challenge for the clinicians, as if left unrelieved, it might cause a delayed recovery of the patient and a prolonged hospital stay. Not much literature is found regarding the peri-articular use of levobupivacaine in patients undergoing TKA. So, we aimed to compare the efficacy of peri-articular infiltration of bupivacaine and levobupivacaine for postoperative pain control in TKA. Methodology: We organised a randomised, prospective, double blind study and enrolled sixty patients undergoing TKA by a single surgeon. Group L (Levobupivacaine) received peri-articular injections with 0.20% levobupivacaine before wound closure and Group B (Bupivacaine) patients received a 0.25% bupivacaine injection. All the cases were performed by a standardized anesthetic technique, postoperative pain control and rehabilitation protocol. Results: Postoperative morphine consumption within first twelve hours was observed to be significantly reduced in Group L (P < 0.05). However, no significant difference was observed in the two groups on comparing postoperative morphine consumption between 12-96 hours. VAS scores were also found to be comparable between the groups. Conclusion: Administration of peri-articular injection with levobupivacaine before the wound closure was shown to be an effective method for postoperative analgesia after TKA with minimal side effects.
Page(s): 315-319
DOI: DOI not available
Published: Journal: Anaesthesia, Pain and Intensive Care, Volume: 20, Issue: 3, Year: 2016
Keywords:
Bupivacaine , Total knee arthroplasty , Levobupivacaine , Periarticular injection
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