Abstract:
Objective: To determine the frequency of TIMI (Thrombolysis in Myocardial Infarction) grade 3 on angiography in patients presenting with acute STEMI who fulfill ECG criteria of successful thrombolysis after being thrombolysed with streptokinase. Methodology: This descriptive study was conducted at Chaudhry Pervaiz Elahi Institute of Cardiology, Multan from August 2013 to March 2014. Patients with acute STEMI who were thrombolysed with streptokinase and whom ECGs were meeting criteria of successful thrombolysis (showing ST segment resolution of50% from J point) were included. These patients under went coronary angiography to evaluate the frequency of TIMI grade 3 flow. Data was analysed using SPSS version 16.Results: A total of 178 patients were studied. Males were 84.8% (n=151). Meanage was 47.06±1.26 years(25-65 years). TIMI grade 3 flow on angiography was achieved in 82.6%(n=147) while 17.4% (n=31) patients did not. There was no statistically difference of TIMI grade 3 between males and females (81.5% vs.88.9%, p=0.348). In comparison to non-diabetics, less number of diabetic patients achieved TIMI grade 3 flow (88.5% vs. 66.7%,p=0.001). Similarly, non hypertensive have got more TIMI grade 3 vs. hypertensive patients(92.2% vs.65.1%,p=0.000). There was no statistical difference between the patients with family history of IHD and those without family history of IHD (74.4% vs.85.2%,p= 0.105). Surprisingly, smokers had got more TIMI grade 3 ascompared to non-smokers (88.1% vs. 75.3%, p = 0.026).Conclusion: We concluded that ECG criteria of successful thrombolysis is very good predictor of infarct related artery patency.
Page(s):
9-12
DOI:
DOI not available
Published:
Journal: Pakistan Heart Journal, Volume: 48, Issue: 1, Year: 2015