Acute lupus haemophagocytic syndrome. | [Biomedica • 2013]

Author(s):

1. Ayesha Ehsan: Department of Haematology, Fatima Memorial Hospital, Lahore, Pakistan

2. Ayaz Lone: Department of Haematology, Fatima Memorial Hospital, Lahore, Pakistan

3. Sumera Farman Raja: Department of Rheumatology, Fatima Memorial Hospital, Lahore, Pakistan

4. Nighat Mir: Department of Rheumatology, Fatima Memorial Hospital, Lahore, Pakistan

5. Sabiha Riaz: Department of Haematology, Fatima Memorial Hospital, Lahore, Pakistan

Abstract:

A 25 year old female who had been on treatment for Systemic Lupus Erythematosus for the last 12 years presented with high grade non-remitting fever and pleural effusion. She had delivered a full term baby girl and soon developed pancytopenia, markedly raised fibrinogen degradation products, deranged coagulation profile, low serum fibrinogen level, raised liver enzymes and grossly raised serum ferritin. Bone marrow examination revealed reactive haemophagocytosis and megaloblastosis. Autoimmune disorders can lead to reactive haemophagocytic syndrome which is a treatable entity even if it presents with life threatening complications.

Page(s): 269-272

DOI: DOI not available

Published: Journal: Biomedica, Volume: 29, Issue: 4, Year: 2013

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