Abstract:
Oats are the fourth most consumed cereal globally that exhibit anextensive therapeutic implications. The significant metabolites credentials of oats include beta-glucan, protein, fatty acids, minerals, phenolic acids, tocols, sterols, avenacosides and AVNs that play a pivotal role in health promotion and appetite management. The primary components of oats that showed an influential impact on appetite hormones are beta-glucan and secondary metabolites. Appetite regulatory hormones are directly associated with hunger, satiety, glucose metabolism and obesity. These hormones include leptin, ghrelin, cholecystokinin (CCK), oxyntomodulin (OXM), glucagon-like receptor-1 (GLP-1), insulin-like peptide-5 (INSLP-5), and peptide YY (PYY). Beta-glucans are natural compounds with no substantial adverse effects that are found to be in two forms, insoluble and soluble. These bioactive forms intend to interact with lipids and bile salts in the intestine and lower cholesterol levels. Oats are considered to be developed as a viable alternative therapy due to its multiple functions and bioactive properties. The beta-glucans are based on their capacity to ferment and create high viscosity solutions in the human colon. These significant molecules are responsible for lowering postprandial glucose and insulin resistances along with the suppression of certain appetite hormones and satiety stimulation. The oat beta-glucan and glycemic management have also shown a strong association as appetite regulating hormones and microbiota in T2DM are particularly being positively provoked via this mechanism. Oats are found to significantly decrease the HbA1c, insulin, C-peptide, homeostatic model assessment (HOMA), Lactobacillus spp. and butyrate-producing bacteria through appetite hormones control. The suppressed levels of leptin, GLP-1, and PYY hormones by oats enhances satiety levels in humans. The positive changes in lipid profile including total cholesterol, Low density lipoproteins, very low density lipoproteins, TAGs, aspartate aminotransferase (AST), alanine aminotransferase (ALT), insulin, hemoglobin A1c (HbA1c), total body fat percentage (TBF), waist and hip circumferences, visceral fat percentage, and systolic blood pressure (SBP) also owe to the combating effects of oats. Hence, oats are rich in macronutrients, soluble fiber, minerals, vitamins, and several phytochemicals that have a positive role in maintaining body weight and BMI, reducing percent body fat, and regulating appetite and energy.
Page(s):
73-73
DOI:
DOI not available
Published:
Journal: Abstract Book on International Conference on Food and Applied Sciences (ICFAS-23) 3-5 August 23, Volume: 0, Issue: 0, Year: 2023
Keywords:
Hunger
,
Betaglucan
,
appetite hormones
,
satiety
,
oats