Author(s):
1. Ahmad Hasan Mufti:
Department of Medical Genetics, Faculty of Medicine, Umm Al-Qura University,Makkah,Saudi Arabia
Abstract:
One of the major genetic factors that is associated with cardiovascular diseases (CVDs) is tissue factor (TF). Studies have investigated this association and identified possible correlation with CVDs and risk factors. Increased expression level of TF has been observed in individuals with high blood glucose level, which could be reduced by controlling glucose level. Furthermore, high cholesterol level has been associated with high TF levels. In addition, high level of TF is reported in obese individuals and those who lack physical activity, and improving these factors lowers TF levels. Therefore, TF has been used as a therapeutic target for reducing the risk of CVDs but with limited success so far. Thus, this study aims to explore the current advances regarding the association of TF with the risk of developing CVDs.
Page(s):
155-159
DOI:
DOI not available
Published:
Journal: International Journal of Biology and Biotechnology, Volume: 19, Issue: 2, Year: 2022
Keywords:
tissue factor
,
Genetics
,
Diabetes
,
Cardiovascular disease
,
hypercholesterolemia
,
Gene
,
coagulation cascade
References:
References are not available for this document.
Citations
Citations are not available for this document.