The effect of Epicardial Adipose Tissue Thickness with Irritable Bowel Syndrome. | [Journal of Pakistan Medical Association • 2018]

Author(s):

1. Yksel Cicek: Department of Cardiology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey

2. Murtaza Emre Durakoglugil: Department of Cardiology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey

3. Halil Rakici: Departments of Gastroenterology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize,

4. Akif Serhat Balcioglu: Department of Cardiology, Alanya Medical and Research Center of Alanya, Baskent University, Antalya, Turkey

5. Hakan Duman: Department of Cardiology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey

6. Turan Erdogan: Department of Cardiology, Recep Tayyip Erdogan University, Faculty of Medicine, Rize, Turkey

Abstract:

Objective: To investigate the association of epicardial adipose tissue thickness with irritable bowel syndrome. Methods: This case-control and observational study was conducted in Recep Tayyip Erdogan University between January and December 2014, and comprised patients of irritable bowel syndrome and healthy controls who underwent a complete transthoracic echocardiographic examination as well as measurements of epicardial adipose tissue. They were screened for psychiatric or organic bowel diseases for the sake of precise diagnosis. Epicardial fat thickness was measured perpendicularly in front of the right ventricular free wall at end-diastole.SPSS 15 was used to analyse the data. Results: Of the 75 subjects, 44(59%) were patients and 31(41%) were controls. There was no statistically significant difference between the groups except epicardial adipose tissue thickness, which was significantly elevated in patients (p<0.001). C-reactive protein was significantly higher in patients (p=0.002). Epicardial adipose tissue (p<0.001) and haematocrit (p<0.05) were independent predictors of irritable bowel syndrome. Conclusion: Increased epicardial adipose tissue thickness, and accompanying low-grade inflammation appeared to be involved in irritable bowel syndrome pathogenesis.

Page(s): 1456-1460

DOI: DOI not available

Published: Journal: Journal of Pakistan Medical Association, Volume: 68, Issue: 10, Year: 2018

Keywords:

Computed tomography , CT scan , Carcinomatosis , Omental biopsy

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