A Antinociceptive activity of methanol extract of Solanum sisymbrifolium Lamk. | Pakistan Journal of Biological Sciences 2005

Author(s)

J. A. Shilpi Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

R. Rouf Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

S. J. Uddin Pharmacy Discipline, Khulna University, Khulna 9208, Bangladesh

M. A. M. Sarker Department of Pharmacology and Therapeutics, Khulna Medical College, Khulna, Bangladesh

A. R. Qamrunnah Biotechnology and Genetic Engineering Discipline, Khulna University, Khulna 9208, Bangladesh

M. M. Ferdous Department of Botany, University of Rajshahi, Rajshahi 6205, Bangladesh

Abstract

The antinociceptive activity of the methanolic extract of the whole plant of Solanum sisymbrifolium Lamk was investigated using acetic acid-induced writhing model in swiss albino mice. At the doses of 125, 250 and 500 mg kg-`body weight, the extract showed 44.19, 59.53 and 73.02% writhing inhibition, respectively in test animals which were comparable to that of standard drug aspirin (85.12%) and the results were statistically significant (p

Publication Details

Page(s) 1123-1125

DOI DOI not available

Published Journal: Pakistan Journal of Biological Sciences, Volume: 8, Issue: 8, Year: 2005

Keywords

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