A Study on a 21years Female Patient with Resected Pituitary Macroadenoma Presented with Persistently Raised Growth Hormone Levels and Resistant Diabetes Mellitus | [Journal of Pakistan Society of Internal Medicine • 2023]

Author(s):

1. Faizan Banaras: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

2. Ramish Fayyaz: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

3. Mahnoor Ashfaq: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

4. Khola Fayaz: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

5. Tehrim Tahir: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

6. Ali Raza: Allied Ayub Teaching Hospital, Abbottabad, KPK, Pakistan

Abstract:

Pituitary neuroendocrine tumors affect round about 5% of the general population. Pituitary macroadenomas have a size greater than 10mm, while microadenoma has a size less than 10mm.4 Acromegaly is a rare but fatal disorder mainly due to excessive growth hormone (GH) production from pituitary adenoma and a secondary rise in IGF-1 levels. It is characterized by physical disfigurement mainly face and limbs. The prevalence of acromegaly is 40 to 70 cases per million inhabitants with an annual incidence rate of 3 to 4 per million.5 The treatment options consist of pituitary surgery with the best approach of endonasal transsphenoidal hypophysectomy. The drugs used for prolactinoma and somatotrophic adenoma are dopamine agonists and somatostatin analogues respectively.

Page(s): 60-62

DOI: DOI not available

Published: Journal: Journal of Pakistan Society of Internal Medicine, Volume: 4, Issue: 1, Year: 2023

Keywords:

Diabetes Mellitus , Pituitary Macroadenoma , dopamine agonists

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