Author(s):
1. Ikram Din Ujjan:
Liaquat University of Medical and Health Sciences, Jamshoro Pakistan
2. Yar Muhammad Waryah:
Liaquat University of Medical and Health Sciences, Jamshoro Pakistan
3. Ali Raza Rajput:
Liaquat University of Medical and Health Sciences, Jamshoro Pakistan
4. Ali Muhammad Waryah:
Liaquat University of Medical and Health Sciences, Jamshoro Pakistan
Abstract:
Objective: This study was aimed to analyze the pattern of viral shedding and correlate it with clinical demographic characteristics. Material and Methods: The nasopharyngeal swabs of suspected patients with COVID-19 were collected. The clinical symptoms and medical history were recorded. RNA was detected by using Real-time PCR for N and Orf1b genes. The viral load was determined by the CT method. Results: Out of a total of 2000 patients, 400 (20%) were found to be positive. Only 22.5% (90/400) patients had variable clinical symptoms, 77.5% (310/ 400) were asymptomatic. Fever, fatigue and loss of taste were the common symptoms in in-patients. Majority of the patients, 52%, were between 21 to 40 years and had viral load between CT values 21 to 30. Male gender was predominant in all the age groups except the oldest age group above 60 years. Orf1b based assay was more sensitive to detect SARS CoV-2 as compared to N gene. Conclusion: This is the first report from Pakistan describing that males of intermediate age were more prone to COVID-19 infection and the Orf1b gene was more sensitive for diagnosis. The findings may be helpful for diagnosis and management of COVID-19 patients.
Page(s):
48-51
DOI:
DOI not available
Published:
Journal: Pakistan Journal of Pathology, Volume: 32, Issue: 2, Year: 2021
Keywords:
SARS CoV2
,
Clinical characteristics
,
Viral shedding
References:
References are not available for this document.
Citations
Citations are not available for this document.