An investigation on the pharmacological activity of an ayurvedic formulation Mahadraksharista. | [Hamdard Medicus • 2007]

Author(s):

1. Sultana Rajia: Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

2. M. Shahabuddin Kabir Choudhuri: Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

3. Mafruhi Sattar: Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

4. Masum Shahriar: Department of Pharmacy, Jahangirnagar University, Dhaka, Bangladesh

Abstract:

In this study an Ayurvedic formulation Mahadraksharista was studied for its pharmacological properties using laboratory mice. There was a constant reduction in food and water intake in Mahadraksharista treated mice, consequently there was also a reduction in urine volume, stool and water content of stool. The Mahadraksharista in a significant extent reduced the intestinal motility. This reduced intestinal motility was further supported by the significant anti-diarrhoeal property of the preparation in castor oil induced diarrhoea test. The formulation markedly increased the latent period of diarrhoea and reduced the purging index value. The Mahadraksharista significantly reduced the onset of sleeping time, but had no effect on the duration of sleeping time.

Page(s): 17-22

DOI: DOI not available

Published: Journal: Hamdard Medicus, Volume: 50, Issue: 3, Year: 2007

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