Aetiology of jaundice in pregnancy | [Pakistan Journal of Medical and Health Sciences • 2021]

Author(s):

1. TANWEER AKHTAR: Department of Obstetrics & Gynaecology, Shaikh Zayed Women Hospital, Shaheed Mohtarma Benazir Bhutto Medical University, Lakana, Pakistan

2. SHAZIA SHAIKH: Department of Obstetrics & Gynaecology, Shaikh Zayed Women Hospital, Shaheed Mohtarma Benazir Bhutto Medical University, Lakana, Pakistan

3. ALI HYDER MUGHERI: Shaheed Mohtarma Benazir Bhutto Medical University, Lakana, Pakistan

4. SANIA PIRZADO: Shaheed Mohtarma Benazir Bhutto Medical University, Lakana, Pakistan

5. NAJIA BHATTI: Department of Obstetrics & Gynaecology, Pir Sayed Abdul Qadir Shah Jilani Institute of Medical Sciences, Gambat, Pakistan

6. WAQAR-UN-NISA AHMED: Department of Obstetrics & Gynaecology, Pir Sayed Abdul Qadir Shah Jilani Institute of Medical Sciences, Gambat, Pakistan

Abstract:

Aim: To investigate the etiology of jaundice in pregnancy. Study design: Cross-sectional, observational study. Place and duration of study: Department of Obstetrics & Gynaecology, Sheikh Zayed Women Hospital Larkana from 1st January 2017 to 31st January 2018. Methodology: Forty patients were recruited. After taken consent form, a proper clinical history, demographic, physical examinations, complications and neonatal outcomes were collected through questionnaire. Etiological investigation of jaundice had been through viral biomarker by enzyme linked immunosorbent assay. Liver enzymes like serum bilirubin, SGT, SGPT, alkaline phosphatase was done by laboratory examination. Results: 53% having age group of 20-30 years (27.6±0.7) belonging to poor socioeconomic status. The statistical outcome indicates that hepatitis E virus is the major etiology of jaundice in pregnant woman 67%. The mean level of serum bilirubin was 9.71±2.8. It was observed that anemia, edema, vomiting, irritation and weakness were more common sign and symptoms in pregnant women. Conclusion: Acute hepatitis E virus infection was the main causative factor.

Page(s): 870-872

DOI: DOI not available

Published: Journal: Pakistan Journal of Medical and Health Sciences, Volume: 15, Issue: 4, Year: 2021

Keywords:

etiology , jaundice , Hepatitis E virus , Acute hepatitis infection

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