Acute oral mucositis during hypo-fractionated radiation in squamous cell carcinoma of oral cavity | [Journal of College of Physicians and Surgeons--Pakistan : JCPSP • 2023]

Author(s):

1. Agha Muhammad Hammad: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

2. Sehrish Abrar: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

3. Rabia Tahseen: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

4. Bilal Mazhar Qureshi: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

5. Asim Hafiz: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

6. Ahmed Nadeem Abbasi: Department of Oncology, The Aga Khan University Hospital,Karachi,Pakistan

Abstract:

Oral mucositis remains a concern in the treatment of head and neck malignancies. This small study included 11 patients treated by hypo-fractionated radiotherapy and assessed for oral mucositis. All patients received a radiation dose of 55 Gy in 20 fractions (2.75 Gy/fraction). At the end of the rst week of radiation, three patients had Grade I oral mucositis. During the last week of radiation, most of the patients developed Grade II and III mucositis, 7 (64%) and 4 (36%), respectively. At one month follow-up, 5 (46%) of them had Grade I, while 2 (18%) had developed Grade II mucositis. At three months, 2 (18%) had Grade I mucositis, and none of the patients showed Grade II/III oral mucositis. Grade II oral mucositis was the most common grade found mainly in the last week of radiation therapy. None had Grade IV oral mucositis.

Page(s): 1460-1462

DOI: 10.29271/jcpsp.2023.12.1460

Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 33, Issue: 12, Year: 2023

Keywords:

Oral carcinoma , Acute oral mucositis , Hypofractioned radiation

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