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Alarming state of emerging resistance in Salmonella typhi to conventional an-tityphoid drugs in the Kharian region.
Author(s):
1. Javaid Usman: Pathology Department, Combined Military Hospital (CMH), Kharian, Pakistan
2. K. A. Karamat: Pathology Department, Combined Military Hospital (CMH), Kharian, Pakistan
3. Tariq Butt: Pathology Department, Combined Military Hospital (CMH), Kharian, Pakistan
Abstract:
Enteric fever remains an important cause of mortality and morbidity in the under developed and the developing countries of the world. Once an illness of the hot weather, it is now endemic in Pakistan throughout the year. After the emergence of chloramphenicol (CAP) resistant Salmonella typhi in Pakistan, this trend has been on the rise. In the Kharian region, about 93% of S. typhi are found resistant to conventional antityphoids (CAP, ampicillin and cotrimoxazole). However, all the isolates remained susceptible to fluoroquinolones (ciprofloxacin and ofloxacin) and third generation cephalosporin (ceftriaxone) except S. paratyphi A which was uniformly sensitive to all the conventional antityphoids, fluoroquinolones and third generation cephalosporins.
Page(s): 30-32
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 6, Issue: 1, Year: 1996
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