The Modified Alternate Healthy Eating Index-2010 and Breast Cancer Risk among Women from Karachi, Pakistan | [Journal of Pakistan Medical Association • 2022]

Author(s):

1. Uzma Shamsi: Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan

2. Tiffany Gill: School of Medicine, University of Adelaide, Australia

3. Shaista Khan: Department of Surgery, Aga Khan University, Karachi, Pakistan.

4. Iqbal Azam: Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan

5. David Callen: School of Medicine, University of Adelaide, Australia

6. Romaina Iqbal: Department of Community Health Sciences, Aga Khan University, Karachi, Pakistan

Abstract:

Objective: To determine any relationship of diet with breast cancer risk. Methods: The case-control study was conducted at Aga Khan University Hospital and the Karachi Institute of Radiation and Nuclear Medicine, Karachi, from February 2015 to July 2017, and comprised of cases with a confi rmed diagnosis of breast cancer and healthy controls. Data was collected using the Alternate Healthy Eating Index 2010, which was modifi ed according to the particular cultural patterns of diet in the Pakistani population. Data was analysed using SPSS 21. Results: Of the 1124 subjects, 374(33.3%) were breast cancer cases and 750(66.7%) were controls. High intake of grains, both whole and refi ned including white rice, was associated with breast cancer (odds ratio: 2.53; 95% confi dence interval: 1.69-3.79; p<0.001). There was no association of breast cancer with Alternate Healthy Eating Index 2010 score (odds ratio: 1.85; 95% confi dence interval: 0.61-1.17; p=0.291). Conclusions: There was found a need for awareness of a healthy diet based on more of whole grains and brown rice replacement with refi ned grains and white rice, respectively. Limiting refi ned carbohydrate intake might be a useful public health message and may reduce breast cancer incidence in the long term.

Page(s): 1289-1293

DOI: 10.47391/JPMA.01276

Published: Journal: Journal of Pakistan Medical Association, Volume: 72, Issue: 7, Year: 2022

Keywords:

diet , Grains , breast cancer , AHEI2010

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