Author(s):
1. Tooba Mehreen:
Department of Critical Care, Shifa International Hospital,Islamabad,Pakistan
2. Sara Saghir Kiani:
Department of Internal Medicine, Shifa International Hospital,Islamabad,Pakistan
Abstract:
Wernicke's encephalopathy (WE) is an acute neurological condition characterized by a triad of ophthalmoplegia, ataxia and altered mental status. The underlying cause is thiamine defi ciency, which may be due to multiple aetiologies. Thiamine is essential for carbohydrate and amino acid metabolism. Its defi ciency shunts glucose to anaerobic pathways producing metabolic abnormalities. Diagnosing WE relies heavily on clinical suspicion. Magnetic Resonance Imaging can show some specifi c fi ndings. We report this case of a 35 year old pregnant woman with gestational diabetes who was admitted in hospital for high blood sugar levels and electrolyte abnormalities. She had a history of ten miscarriages. From undergoing laparoscopic cholecystectomy for intractable vomiting to spontaneous expulsion of the foetus to being intubated for acidosis, her hospital stay was prolonged and eventful. Although the cause of her repeated miscarriages could not be established despite extensive workup, thiamine defi ciency leading to Wernicke's encephalopathy was the most probable cause.
Page(s):
550-553
DOI:
DOI not available
Published:
Journal: Journal of Pakistan Medical Association, Volume: 72, Issue: 3, Year: 2022
Keywords:
Lactic acidosis
,
Metabolic encephalopathy
,
Hyperemesis gravidarum
,
Wernickes encephalopathy
,
Thiamine
References:
References are not available for this document.
Citations
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