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A study on the frequency of Hyponatremia and Electrocardiographic changes in patients with Subarachnoid Hemorrhage in Razi and Imam Hospitals at Tabriz.
Author(s):
1. H. Karbakhshzadeh: Department of Neurology, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
2. M Nikanfar: Department of Neurology, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran
Abstract:
Subarachnoid hemorrhage (SAH) usually is caused by sudden rupture of congenital intracerebral aneurysms and at times due to other causes. Hyponatremia (blood Na lower than 135mEg/L) is one of the complications of SAH in acute phase of the disease. According to some studies the cause of this finding is elevated atrial natriuretic peptide (ANP) which leads to water and salt diuresis in kidneys and decrease in blood solutes level. Along with this , after subarachnoid hemorrhage, ECG changes may appear. The pattern of these changes is similar to changes seen in coronary heart disease; elevated cardiac enzymes and disorders in movements of heart walls. This study was carried on between Oct, 2000 to Oct. 2001. Frequency of hyponatremia and ECG changes were  investigated in 50 SAH patients in Razi and Imam Hospitals, the diagnosis of SAH was confirmed by brain CT scan, Lumbar puncture and clinical findings. 50 cases were studied (15 males & 35 females) most of them were in 31-59 years age group. The results revealed that 19 (39%) patients had hyponatremia (15 females and 4 males). ECG changes were found in 42 patients (84%). Including inverted T and tented T waves, elevated and depressed ST segment, biphasic and flat T, prominent U wave, pathological Q wave. The comparison between the results of hyponatremia in our study and previous studies did not show significant difference (P=0.233).
Page(s): 1-5
DOI: DOI not available
Published: Journal: Pakistan Journal of Neurological Sciences, Volume: 9, Issue: 1--2, Year: 2003
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