Abstract:
A six month study on three different anti-tubercular regimens was carried out in 160 patients between 19-60 years of age in the Gulab Devi Chest Hospital, Lahore from June 1980 to October 1981. This hospital has existed since 1934 and caters to patients suffering from chest diseases, mostly pulmonary tuberculosis. The patients selected for the trial had a positive sputum smear, clinical and radiological evidence of pulmonary tuberculosis and no other concomitant disease. Patients were hospitalized for the first three months and then treated on an outpatient basis for the following three months. Streptomycin, isoniazid, pyrazinamide and rifampicin were given in three different combinations. All patients showed a marked improvement clinically, radiologically, in weight gain and sputum conversion except six who had to stop the therapy due to side effects. 134 patients completed the trial with a few of them having untoward effects of a mild nature, such as joint pains, peripheral neuritis and a slight impairment of the liver function tests. The six months short course chemotherapy proved highly effective and advantageous (JPMA 33:243, 1983).
Page(s):
9-14
DOI:
DOI not available
Published:
Journal: Challenge, Volume: 25, Issue: 2, Year: 1984