Utility of Dermoscopy and Interpretation of Dermoscopic Findings in Stable and Progressing Lesions of Vitiligo | [Journal of the College of Physicians and Surgeons Pakistan • 2025]

Author(s):

1. Sara Shafqat: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

2. Atiya Rahman: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

3. Zarin Manzoor: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

4. Shakila Junaid: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

5. Sidra Anwer: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

6. Janta Kumari: Department of Dermatology, PNS Shifa Hospital,Karachi,Pakistan

Abstract:

Objective: To identify the various dermoscopic patterns present in vitiligo and its predictive value in determining the stability of the disease. Study Design: Cross-sectional study. Place and Duration of the Study: Department of Dermatology, PNS Shifa Hospital, Karachi, Pakistan, from October 2023 to July 2024. Methodology: A total of 80 clinically diagnosed patients of vitiligo, of either gender, with stable and progressing vitiligo, having age e18 years, were included. Dermoscopic examination of vitiligo lesions was done to evaluate the clinical stability of the lesions. SPSS version 26 was used to analyse the data. The dermoscopic ndings of stable and progressing vitiligo were compared using the Chi-square test and Fisher s exact test. Results: Out of the 80 patients who were clinically diagnosed with vitiligo, 56 (70%) were women and 24 (30%) were men. The patients' average age was 31.94 ± 8.185 years. Approximately 38 (47.5%) patients had stable vitiligo, while 42 (52.5%) had progressing vitiligo. The dermoscopic patterns included perifollicular depigmentation in 15%, perifollicular hyperpigmentation in 33%, perilesional/marginal hyperpigmentation in 8%, intra/perilesional erythema with telangiectasia in 19%, trichrome pattern in 26%, leucotrichia in 14%, starburst appearance in 24%, comet tail appearance in 26%, and minor Koebner s phenomenon in 33.75% cases. Comparison of ndings between stableversus progressing vitiligo showed signi cant di erence with a p-value of <0.05. Conclusion: Speci c dermoscopic patterns can be utilised to ascertain disease activity and accordingly decide on the management protocol.

Page(s): 693-697

DOI: 10.29271/jcpsp.2025.06.693

Published: Journal: Journal of the College of Physicians and Surgeons Pakistan, Volume: 35, Issue: 06, Year: 2025

Keywords:

dermoscopy , dermatoscopy , Stable vitiligo , Dermoscopic patterns , Dermatoscopic patterns , Progressing vitiligo

References:

[1] Hedayat K,Karbakhsh M,Ghiasi M,Goodarzi A,Fakour Y,Akbari Z .2016 .Quality of life in patients with vitiligo: A cross-sectional study based on vitiligo quality of life index (VitiQoL). Health Qual Life Outcomes, 10 : 86.

[2] Godinez-Chaparro JA,Roldan-Marin R,Vidaurri-de la Cruz H,Soto-Mota LA,Ferez K. .2023 .Dermatoscopic patterns in vitiligo. Dermatol Pract Concept, 10(4) : .

[3] Jha AK,Sonthalia S,Lallas A,Chaudhary RKP .2018 .Dermoscopy in vitiligo: Diagnosis and beyond. Int J Dermatol, 10(1) : 50-4.

[4] Cabrera R,Recule F,Hojman L,Larrondo J .2019 .Follicular vitiligo: Dermatoscopic features of a new subtype of vitiligo. Ann Bras Dermatol, 4841(1) : 20198086-1.

[5] Sindhuri G,Karim S,Patel P,Nadkarni N,Patil S,Godse K. .2024 .Dermatoscope as a tool to determine the stability of vitiligo. IP Indian J Clin Exp, 034(2) : 187-91.

[6] Badad AS,Chowdry A,Hogade A . .A study of role of dermoscopy in disease activity of vitiligo patients. Int J, : .

[7] Wang LM,Lu WJ,Yuan JT,Zeng BB,Li D,Zhang F .2018 .Utility of dermoscopy for evaluating the therapeutic e cacy of tacrolimus ointment plus 308-nm excimer laser combination therapy in localized vitiligo patients. Exp Ther Med, 5911(4) : 3981-8.

[8] ElkazzazAzza KH,Heba Allah SEB,Hesham NK .2022 .Role of dermoscopy in the diagnosis of vitiligo and evaluating its clinical stability. Menouf Med J, 35(3) : 23.

[9] Haldar SS,Nischal KC,Khopkar US,Text Short .2012 .Trichoscopy in Diseases of the Brown Skin: Atlas. , : 16.

[10] Gutte R,Khopkar US,Text Short .2012 .Trichoscopy in Diseases of the Brown Skin: Atlas. , : 112-3.

[11] Chuh AA,Zawar V .2004 .Demonstration of residual perifollicular pigmentation in localized vitilig o-A reverse and novel application of digital epiluminescence dermoscopy. Comput Med Imaging Graph, 03(4) : 213-7.

[12] Purnima G,Gudivada NAT,Narasimharao TV .2017 .Dermoscopy A tool to assess stability in vitiligo. Int J Contemp Med Res, 424183(10) : 2066-8.

[13] Jha AK,Sonthalia S,Lallas A .2017 .Dermoscopy as an evolving tool to assess vitiligo activity. J Am Acad Dermatol, 12(5) : 1017-9.

[14] Nirmal B,Antonisamy B,Peter CD,George L,George AA,Dinesh GM .2019 .Cross-sectional study of dermatoscopic ndings in relation to activity in vitiligo: BPLeFoSK criteria for stability. J Cutan Aesthet Surg, 75(1) : 18.

[15] Nirmal B .2021 .Utility of blue light in dermoscopy for diagnosing stable lesions in vitiligo. Dermatol Pract Concept, 10(1) : .

[16] Meng R,Zhao G,Cai RK .2009 .Application of polarized light dermoscopy in the early diagnosis of vitiligo and its di erential diagnosis from other depigmented diseases. Chin J Dermatol, 42(12) : 810-3.

[17] Suresh MS,Divya KS,Sambangi J,Guruprasad P .2024 .Crosssectional descriptive study of the utility of dermoscopy in assessing the activity and stability of vitiligo. Dermatol Pract Concept, 10(4) : .

[18] Guneet A,Jasleen K,Komalpreet K. .2022 .An emerging armamentarium in diagnosis and activity assessment. Pigment Int, 10(1) : 24-32.

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