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Treatment of cutaneous leishmaniasis with photodynamic therapy: The first case report from Khyber Pakhthunkhwa (KPK), Swat Pakistan
Author(s):
1. Aakifullah Khan: Swat Institute of Nuclear Medicine and Radiotherapy (SINOR), Swat, Pakistan
2. Karim Khan: Department of Physics, University of Malakand, Chakdara, KPK, Pakistan
3. Ghufran Biradar: Swat Institute of Nuclear Medicine and Radiotherapy (SINOR), Swat, Pakistan
4. Moiz Khan: Peshawar Medical College, Peshawar KPK, Pakistan.
Abstract:
Cutaneous Leishmaniasis (CL), the most common subtype of leishmaniasis, is a vector borne disease transmitted by sand fly. Herein, we report a case of CL being treated for the first time with photodynamic therapy (PDT) in KPK, Pakistan. A 55-year-old female patient presented with a single chronic disfiguring ulcerated lesion on the chin. The patient had received pentavalent antimoniate for the last 2 years, with no satisfactory outcome. We treated the patient with methylaminolevulinate based PDT and observed complete response after three sessions of the PDT treatment, each with a light energy dose of 75 J/cm2. The patient has remained disease-free for over 2 years. This study demonstrates the promising role of PDT in the treatment of CL.
Page(s): 120-124
DOI: DOI not available
Published: Journal: Journal of Pakistan Association of Dermatologists, Volume: 31, Issue: 1, Year: 2021
Keywords:
Cutaneous leishmaniasis , photosensitizer , Photodynamic therapy , methylaminolevulinate , pentavalent antimoniate
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