Wildlife as a Source of SARS-CoV-2 Evolution- A Review | [Pakistan Journal of Zoology • 2022]

Author(s):

1. Muhammad Altaf: Department of Zoology, Women University of Azad Jammu and Kashmir, Bagh, Pakistan

2. Arshad Mahmood Abbasi: Department of Environment Sciences, COMSATS University Islamabad, Abbottabad Campus 22060, Pakistan

3. Muhammad Shoaib Amjad: Department of Botany, Women University of Azad Jammu and Kashmir, Bagh, Pakistan

4. Sadia Naseer: Department of Zoology, Women University of Azad Jammu and Kashmir, Bagh, Pakistan

5. Muhammad Umair: School of Agriculture and Biology, Shanghai Jiao Tong University, Shanghai, China

Abstract:

Coronavirus consists of single-stranded, enveloped and RNA virus, largest genome among all RNA viruses and has 4 proteins i.e. envelope, spike, nucleocapsid and membrane. Coronaviruses are classified into 4 genera: Alphacoronavirus, Betacoronavirus, Gammacoronavirus and Deltacoronavirus. Betacoronavirus most probably originated from bats and the virus may have jumped to avian species and evolved as Deltacoronavirus group. The avian coronaviruses jumped among other avian species, giving rise to Gammacoronavirus from Deltacoronavirus, while Betacoronavirus may have given rise to Alphacoronavirus. It is known that SARS-CoV-2 belongs to Betacoronavirus. This most similar virus is verified in bat and Malayan Pangolin. Analysis showed that SARS-CoV-2 most probably originated by recombination of both bat and pangolin viruses. Viral protein seroconversion and viral specific nucleotide positive documented in all COVID-19 patients tested provides confirmation of a link between the presence of this virus and the disease.

Page(s): 1899-1904

DOI: 10.17582/journal.pjz/20200510100555

Published: Journal: Pakistan Journal of Zoology, Volume: 54, Issue: 4, Year: 2022

Keywords:

COVID19 , SARSCoV2 , Zoonoses , Bats , Pangolin

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