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Vitamin B12 Deficiency in Patients with Type-II Diabetes Mellitus Using Metformin
Author(s):
1. Haseeb ul Hassan: Abbas Institute of Medical Sciences Muzaffarabad Azad Kashmir.Pakistan
2. Idrees Zafar: Abbas Institute of Medical Sciences Muzaffarabad Azad Kashmir.Pakistan
3. Hamza Azhar: Abbas Institute of Medical Sciences Muzaffarabad Azad Kashmir.Pakistan
4. Noor-us-Sabahat: CMH Muzafarabad Azad Kashmir.Pakistan
5. Khizra Manzoor: Abbas Institute of Medical Sciences Muzaffarabad Azad Kashmir.Pakistan
6. Maryum Saleem Raja: Abbas Institute of Medical Sciences Muzaffarabad Azad Kashmir.Pakistan
Abstract:
To find out the prevalence of vitamin B12 deficiency among the patients with type-II diabetes mellitus using metformin. Study Design: Cross-sectional study Place and Duration of Study: This study was conducted at the Abbasi Institute of Medical Sciences Muzaffarabad. Study was completed in six months duration from July 2021 to December 2021 for a period of six months. Materials and Methods: All previously diagnosed cases with type-II diabetes mellitus using metformin for more than six months duration was included in this study. Blood level of vitamin B12 was measured in all cases. SPSS-17 software was used for data analysis. P-value <0.05 was taken statistically significant. Results: Total 200 cases were studied including 127(63.5%) male and 73(36.5%) female cases. 23% diabetic patients using metformin were having vit-B12 deficiency with the blood level <150 pg/ml. age range of the patients was 30-75 years with mean age of 45.7 ± 5.8 years. Smokers were having more incidence of vit-B12 deficiency than non-smokers. Use of multivitamins prevent B-12 deficiency. Conclusion: Use of metformin in diabetes mellitus is strongly associated with B-12 deficiency, so endocrinologist and physician should evaluate diabetic patients for B-12 deficiency and treat it properly.
Page(s): 122-124
DOI: DOI not available
Published: Journal: Medical Forum, Volume: 33, Issue: 3, Year: 2022
Keywords:
Diabetes Mellitus , Diabetes Mellitus , Vitamin B12 , metformin
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