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Tailored metabolic workup for urolithiasis - the debate continues.
Author(s):
1. M. Hammad Ather: Department of Surgery, The Aga Khan University Hospital, Karachi.
2. Imran Siddiqui: Department of Pathology, The Aga Khan University Hospital, Karachi
3. Tahmeena Siddiqui: Department of Biochemistry, Karachi Medical and Dental College (KMDC), Karachi
4. M. Nasir Sulaiman: Department of Surgery, The Aga Khan University Hospital, Karachi.
Abstract:
Urolithiasis is one of the commonest afflictions of the urinary tract. Stones are of various chemical compositions, some share some common etiology; but most are specific to the structure and composition of stone. In view of highly recurrent nature of this condition, it is logical to have strategies for prevention. However, due to multiple factors most patients receive no or fragmented information on prevention. The current controversy is to the extent of metabolic workup in adult first time stone former. This requires longitudinal studies to show benefit in prevention strategies. Patients at high risk can have recurrence in weeks to years, depending upon the composition and attending risk factor. They should be targeted with concentric and tailored prevention protocols. The major urological guidelines (EAU and AUA) recommend basic stone workup for all patients. However, indication for detailed workup are less well documented, so one potential solution is to tailor metaphylaxis strategies for individual patient.
Page(s): 101-104
DOI: DOI not available
Published: Journal: Journal of College of Physicians and Surgeons--Pakistan : JCPSP, Volume: 27, Issue: 2, Year: 2017
Keywords:
Urolithiasis Metabolic workup Hyperoxaluria Hyperuricemia Hypocitraturia
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